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Targeting Prefrontal Cortical Systems for Drug Development: Potential Therapies for Cognitive Disorders

Medications to treat cognitive disorders are increasingly needed, yet researchers have had few successes in this challenging arena. Cognitive abilities in primates arise from highly evolved N-methyl-d-aspartate (NMDA) receptor circuits in layer III of the dorsolateral prefrontal cortex. These circui...

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Detalhes bibliográficos
Publicado no:Annu Rev Pharmacol Toxicol
Main Authors: Arnsten, Amy F.T., Wang, Min
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734124/
https://ncbi.nlm.nih.gov/pubmed/26738476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-pharmtox-010715-103617
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