Signatures in Simian Immunodeficiency Virus SIVsmE660 Envelope gp120 Are Associated with Mucosal Transmission but Not Vaccination Breakthrough in Rhesus Macaques

Mucosal surfaces are vulnerable to human immunodeficiency virus (HIV)/simian immunodeficiency virus (SIV) infection and thus are key sites for eliciting vaccine-mediated protection. Vaccine protocols carried out at the Yerkes Primate Research Center utilized SIVmac239-based immunization strategies w...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Smith, S. Abigail, Kilgore, Katie M., Kasturi, Sudhir Pai, Pulendran, Bali, Hunter, Eric, Amara, Rama R., Derdeyn, Cynthia A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Pathogenesis and Immunity
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4734005/
https://ncbi.nlm.nih.gov/pubmed/26676777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02711-15
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