Characterization and Implementation of a Diverse Simian Immunodeficiency Virus SIVsm Envelope Panel in the Assessment of Neutralizing Antibody Breadth Elicited in Rhesus Macaques by Multimodal Vaccines Expressing the SIVmac239 Envelope

Antibodies that can neutralize diverse viral strains are likely to be an important component of a protective human immunodeficiency virus type 1 (HIV-1) vaccine. To this end, preclinical simian immunodeficiency virus (SIV)-based nonhuman primate immunization regimens have been designed to evaluate a...

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Publicado en:J Virol
Autores principales: Kilgore, Katie M., Murphy, Megan K., Burton, Samantha L., Wetzel, Katherine S., Smith, S. Abigail, Xiao, Peng, Reddy, Sharmila, Francella, Nicholas, Sodora, Donald L., Silvestri, Guido, Cole, Kelly S., Villinger, Francois, Robinson, James E., Pulendran, Bali, Hunter, Eric, Collman, Ronald G., Amara, Rama R., Derdeyn, Cynthia A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Vaccines and Antiviral Agents
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4524250/
https://ncbi.nlm.nih.gov/pubmed/26018167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01221-14
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