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In Vitro Reactivation of Replication-Competent and Infectious HIV-1 by Histone Deacetylase Inhibitors

The existence of long-lived HIV-1-infected resting memory CD4 T cells is thought to be the primary obstacle to HIV-1 eradication. In the search for novel therapeutic approaches that may reverse HIV-1 latency, inhibitors of histone deacetylases (HDACis) have been tested to reactivate HIV-1 replicatio...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Banga, Riddhima, Procopio, Francesco Andrea, Cavassini, Matthias, Perreau, Matthieu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733986/
https://ncbi.nlm.nih.gov/pubmed/26656693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02359-15
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