A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies

Previous studies have shown that sera from HIV-1-infected individuals contain antibodies able to mediate antibody-dependent cellular cytotoxicity (ADCC). These antibodies preferentially recognize envelope glycoprotein (Env) epitopes induced upon CD4 binding. Here, we show that a highly conserved try...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Ding, Shilei, Veillette, Maxime, Coutu, Mathieu, Prévost, Jérémie, Scharf, Louise, Bjorkman, Pamela J., Ferrari, Guido, Robinson, James E., Stürzel, Christina, Hahn, Beatrice H., Sauter, Daniel, Kirchhoff, Frank, Lewis, George K., Pazgier, Marzena, Finzi, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Pathogenesis and Immunity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4733974/
https://ncbi.nlm.nih.gov/pubmed/26637462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02779-15
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