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Valve endothelial cell-derived Tgfβ1 signaling promotes nuclear localization of Sox9 in interstitial cells associated with attenuated calcification

OBJECTIVE: Aortic valve disease, including calcification affects more than 2% of the human population and is caused by complex interactions between multiple risk factors including genetic mutations, the environment and biomechanics. At present, there are no effective treatments other than surgery an...

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Xehetasun bibliografikoak
Argitaratua izan da:Arterioscler Thromb Vasc Biol
Egile Nagusiak: Huk, Danielle J, Austin, Blair F., Horne, Tori E., Hinton, Robert B., Ray, William C., Heistad, Donald D., Lincoln, Joy
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2015
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732913/
https://ncbi.nlm.nih.gov/pubmed/26634652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306091
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