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Valve endothelial cell-derived Tgfβ1 signaling promotes nuclear localization of Sox9 in interstitial cells associated with attenuated calcification

OBJECTIVE: Aortic valve disease, including calcification affects more than 2% of the human population and is caused by complex interactions between multiple risk factors including genetic mutations, the environment and biomechanics. At present, there are no effective treatments other than surgery an...

Täydet tiedot

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Bibliografiset tiedot
Julkaisussa:Arterioscler Thromb Vasc Biol
Päätekijät: Huk, Danielle J, Austin, Blair F., Horne, Tori E., Hinton, Robert B., Ray, William C., Heistad, Donald D., Lincoln, Joy
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2015
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732913/
https://ncbi.nlm.nih.gov/pubmed/26634652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.115.306091
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