Sox9 Transcriptionally Represses Spp1 to Prevent Matrix Mineralization in Maturing Heart Valves and Chondrocytes

Sox9 is an SRY-related transcription factor required for expression of cartilaginous genes in the developing skeletal system and heart valve structures. In contrast to positively regulating cartilaginous matrix, Sox9 also negatively regulates matrix mineralization associated with bone formation. Whi...

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Detaylı Bibliyografya
Asıl Yazarlar: Peacock, Jacqueline D., Huk, Danielle J., Ediriweera, Hasini N., Lincoln, Joy
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2011
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3202586/
https://ncbi.nlm.nih.gov/pubmed/22046352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026769
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