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Prenatal Nicotinic Exposure Upregulates Pulmonary C-fiber NK1R Expression to Prolong Pulmonary C-fiber-Mediated Apneic Response

Prenatal nicotinic exposure (PNE) prolongs bronchopulmonary C-fiber (PCF)-mediated apneic response to intra-atrial bolus injection of capsaicin in rat pups. The relevant mechanisms remain unclear. Pulmonary substance P and adenosine and their receptors (neurokinin-A receptor, NK1R and ADA(1) recepto...

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Detalhes bibliográficos
Publicado no:Toxicol Appl Pharmacol
Main Authors: Zhao, Lei, Zhuang, Jianguo, Zang, Na, Lin, Yong, Lee, Lu-Yuan, Xu, Fadi
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732869/
https://ncbi.nlm.nih.gov/pubmed/26524655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.taap.2015.10.023
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