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Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation

Modern enzymes are highly optimized biocatalysts that process their substrates with extreme efficiency. Many enzymes catalyze more than one reaction; however, the persistence of such ambiguities, their consequences and evolutionary causes are largely unknown. As a paradigmatic case, we study the his...

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Detalhes bibliográficos
Publicado no:PLoS Genet
Main Authors: Plach, Maximilian G., Reisinger, Bernd, Sterner, Reinhard, Merkl, Rainer
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732765/
https://ncbi.nlm.nih.gov/pubmed/26824644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1005836
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