Involvement of oxidative stress and caspase 2-mediated intrinsic pathway signaling in age-related increase in muscle cell apoptosis in mice

Apoptosis has been implicated as a mechanism of loss of muscle cells in normal aging and plays an important role in age-related sarcopenia. To test the hypothesis that caspase 2 and c-Jun NH(2)-terminal kinase (JNK)-mediated intrinsic pathway signaling contribute to skeletal muscle cell apoptosis in...

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Vydáno v:Apoptosis
Hlavní autoři: Braga, Melissa, Sinha Hikim, Amiya P., Datta, Sanjit, Ferrini, Monica G., Brown, Danielle, Kovacheva, Ekaterina L., Gonzalez-Cadavid, Nestor F., Sinha-Hikim, Indrani
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732709/
https://ncbi.nlm.nih.gov/pubmed/18461459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-008-0216-7
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