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Testosterone Supplementation Reverses Sarcopenia in Aging through Regulation of Myostatin, c-Jun NH(2)-Terminal Kinase, Notch, and Akt Signaling Pathways
Aging in rodents and humans is characterized by loss of muscle mass (sarcopenia). Testosterone supplementation increases muscle mass in healthy older men. Here, using a mouse model, we investigated the molecular mechanisms by which testosterone prevents sarcopenia and promotes muscle growth in aging...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Endocrine Society
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2817626/ https://ncbi.nlm.nih.gov/pubmed/20022929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2009-1177 |
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