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Testosterone is essential for skeletal muscle growth in aged mice in a heterochronic parabiosis model
As humans age, they lose both muscle mass and strength (sarcopenia). Testosterone, a circulating hormone, progressively declines in aging and is associated with loss of muscle mass and strength. Joining of a young and old mouse (heterochronic parabiosis) activates Notch signaling and restores muscle...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4149819/ https://ncbi.nlm.nih.gov/pubmed/24859218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-014-1900-2 |
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