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Testosterone is essential for skeletal muscle growth in aged mice in a heterochronic parabiosis model

As humans age, they lose both muscle mass and strength (sarcopenia). Testosterone, a circulating hormone, progressively declines in aging and is associated with loss of muscle mass and strength. Joining of a young and old mouse (heterochronic parabiosis) activates Notch signaling and restores muscle...

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Main Authors: Sinha, Indranil, Sinha-Hikim, Amiya P., Wagers, Amy J., Sinha-Hikim, Indrani
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4149819/
https://ncbi.nlm.nih.gov/pubmed/24859218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00441-014-1900-2
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