Structural Basis for Molecular Discrimination by a 3’,3’-cGAMP Sensing Riboswitch

Cyclic dinucleotides are second messengers that target the adaptor STING and stimulate the innate immune response in mammals. Besides protein receptors, there are bacterial riboswitches that selectively recognize cyclic dinucleotides. We recently discovered a natural riboswitch that targets 3’,3’-cG...

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Udgivet i:Cell Rep
Main Authors: Ren, Aiming, Wang, Xin C., Kellenbeger, Colleen A., Rajashankar, Kanagalaghatta R., Jones, Roger, Hammond, Ming C., Patel, Dinshaw J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732562/
https://ncbi.nlm.nih.gov/pubmed/25818298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.004
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