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Global RNA Fold and Molecular Recognition for a pfl Riboswitch Bound to ZMP, a Master Regulator of One-Carbon Metabolism

ZTP, the pyrophosphorylated analog of ZMP (5- amino-4-imidazole carboxamide ribose-5′-monophosphate), was identified as an alarmone that senses 10-formyl-tetrahydroflate deficiency in bacteria. Recently, a pfl riboswitch was identified that selectively binds ZMP and regulates genes associated with p...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Ren, Aiming, Rajashankar, Kanagalaghatta R., Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4685959/
https://ncbi.nlm.nih.gov/pubmed/26118534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.05.016
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