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Structural Basis for Molecular Discrimination by a 3’,3’-cGAMP Sensing Riboswitch

Cyclic dinucleotides are second messengers that target the adaptor STING and stimulate the innate immune response in mammals. Besides protein receptors, there are bacterial riboswitches that selectively recognize cyclic dinucleotides. We recently discovered a natural riboswitch that targets 3’,3’-cG...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Ren, Aiming, Wang, Xin C., Kellenbeger, Colleen A., Rajashankar, Kanagalaghatta R., Jones, Roger, Hammond, Ming C., Patel, Dinshaw J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732562/
https://ncbi.nlm.nih.gov/pubmed/25818298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.03.004
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