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LPS impairs oxygen utilization in epithelia by triggering degradation of the mitochondrial enzyme Alcat1
Cardiolipin (also known as PDL6) is an indispensable lipid required for mitochondrial respiration that is generated through de novo synthesis and remodeling. Here, the cardiolipin remodeling enzyme, acyl-CoA:lysocardiolipin-acyltransferase-1 (Alcat1; SwissProt ID, Q6UWP7) is destabilized in epitheli...
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Опубликовано в: : | J Cell Sci |
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Главные авторы: | , , , , , , , , , , , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
The Company of Biologists Ltd
2016
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4732295/ https://ncbi.nlm.nih.gov/pubmed/26604221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.176701 |
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