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Orc5 induces large-scale chromatin decondensation in a GCN5-dependent manner
In eukaryotes, origin recognition complex (ORC) proteins establish the pre-replicative complex (preRC) at the origins, and this is essential for the initiation of DNA replication. Open chromatin structures regulate the efficiency of preRC formation and replication initiation. However, the molecular...
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| Veröffentlicht in: | J Cell Sci |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
The Company of Biologists Ltd
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4732289/ https://ncbi.nlm.nih.gov/pubmed/26644179 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178889 |
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