In TNF-stimulated cells, RIPK1 promotes cell survival by stabilizing TRAF2 and cIAP1, which limits induction of non-canonical NF-κB and activation of caspase-8.

Ítems similars

• In TNF-stimulated Cells, RIPK1 Promotes Cell Survival by Stabilizing TRAF2 and cIAP1, which Limits Induction of Non-canonical NF-κB and Activation of Caspase-8
  per: Gentle, Ian E., et al.
  Publicat: (2011)
• Tumor necrosis factor (TNF) signaling, but not TWEAK (TNF-like weak inducer of apoptosis)-triggered cIAP1 (cellular inhibitor of apoptosis protein 1) degradation, requires cIAP1 RING dimerization and E2 binding.
  per: Feltham, Rebecca L., et al.
  Publicat: (2017)
• Crystal structures of the TRAF2: cIAP2 and the TRAF1: TRAF2: cIAP2 complexes – affinity, specificity and regulation
  per: Zheng, Chao, et al.
  Publicat: (2010)
• Tumor Necrosis Factor (TNF) Signaling, but Not TWEAK (TNF-like Weak Inducer of Apoptosis)-triggered cIAP1 (Cellular Inhibitor of Apoptosis Protein 1) Degradation, Requires cIAP1 RING Dimerization and E2 Binding
  per: Feltham, Rebecca, et al.
  Publicat: (2010)
• Molecular determinants of Smac mimetic induced degradation of cIAP1 and cIAP2
  per: Darding, M, et al.
  Publicat: (2011)