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Characterization of Tiki, a New Family of Wnt-specific Metalloproteases
The Wnt family of secreted glycolipoproteins plays pivotal roles in development and human diseases. Tiki family proteins were identified as novel Wnt inhibitors that act by cleaving the Wnt amino-terminal region to inactivate specific Wnt ligands. Tiki represents a new metalloprotease family that is...
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| Udgivet i: | J Biol Chem |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4732225/ https://ncbi.nlm.nih.gov/pubmed/26631728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.677807 |
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