Tiki1 is required for head formation via Wnt cleavage-oxidation and inactivation

Secreted Wnt morphogens are signaling molecules essential for embryogenesis, pathogenesis, and regeneration, and require distinct modifications for secretion, gradient formation and/or activity. Whether Wnt proteins can be post-translationally inactivated during development/homeostasis is unknown. H...

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Autors principals: Zhang, Xinjun, Abreu, Jose Garcia, Yokota, Chika, MacDonald, Bryan T., Singh, Sasha, Coburn, Karla Loureiro Almeida, Cheong, Seong-Moon, Zhang, Mingzi M., Ye, Qi-Zhuang, Hang, Howard C., Steen, Hanno, He, Xi
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3383638/
https://ncbi.nlm.nih.gov/pubmed/22726442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2012.04.039
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