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The TIKI/TraB/PrgY family: A common protease fold for cell signaling from bacteria to metazoa?
We report that the metazoan Wnt protease and signaling inhibitor TIKI shares sequence homology with bacterial TraB/PrgY proteins, inhibitors of pheromone signaling essential for propagation of antibiotic resistance. Our analysis suggests that these proteins represent an ancient metalloprotease clan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2013
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3794667/ https://ncbi.nlm.nih.gov/pubmed/23673329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2013.04.019 |
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