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O-Linked β-N-acetylglucosamine (O-GlcNAc) Acts as a Glucose Sensor to Epigenetically Regulate the Insulin Gene in Pancreatic Beta Cells

The post-translational protein modification O-linked β-N-acetylglucosamine (O-GlcNAc) is a proposed nutrient sensor that has been shown to regulate multiple biological pathways. This dynamic and inducible enzymatic modification to intracellular proteins utilizes the end product of the nutrient sensi...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Durning, Sean P., Flanagan-Steet, Heather, Prasad, Nripesh, Wells, Lance
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732198/
https://ncbi.nlm.nih.gov/pubmed/26598517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.693580
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