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Functional O-GlcNAc modifications: Implications in molecular regulation and pathophysiology

O-linked β-N-acetylglucosamine (O-GlcNAc) is a regulatory post-translational modification of intracellular proteins. The dynamic and inducible cycling of the modification is governed by O-GlcNAc transferase (OGT) and O-GlcNAcase (OGA) in response to UDP-GlcNAc levels in the hexosamine biosynthetic p...

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Detalhes bibliográficos
Publicado no:Crit Rev Biochem Mol Biol
Main Authors: Vaidyanathan, Krithika, Durning, Sean, Wells, Lance
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4912837/
https://ncbi.nlm.nih.gov/pubmed/24524620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10409238.2014.884535
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