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Multiple Tissue-specific Roles for the O-GlcNAc Post-translational Modification in the Induction of and Complications Arising from Type II Diabetes

In this minireview, we will highlight work in the last 30 years that has clearly demonstrated that the O-GlcNAc modification is nutrient-responsive and plays multiple roles in metabolic regulation of signaling and gene expression. Further, we will examine recent studies that have investigated the im...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Vaidyanathan, Krithika, Wells, Lance
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4263854/
https://ncbi.nlm.nih.gov/pubmed/25336652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R114.591560
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