Caricamento...
Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response
One of the hallmark mechanisms activated by type I interferons (IFNs) in human tissues involves cleavage of intracellular RNA by the kinase homology endoribonuclease RNase L. We report 2.8 and 2.1 angstrom crystal structures of human RNase L in complexes with synthetic and natural ligands and a frag...
Salvato in:
| Pubblicato in: | Science |
|---|---|
| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731867/ https://ncbi.nlm.nih.gov/pubmed/24578532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1249845 |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|