Quantitative Analysis of Global Proteome and Lysine Acetylome Reveal the Differential Impacts of VPA and SAHA on HL60 Cells

Valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA) are both HDAC inhibitors (HDACi). Previous studies indicated that both inhibitors show therapeutic effects on acute myeloid leukaemia (AML), while the differential impacts of the two different HDACi on AML treatment still remains elusive...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Zhu, Xiaoyu, Liu, Xin, Cheng, Zhongyi, Zhu, Jun, Xu, Lei, Wang, Fengsong, Qi, Wulin, Yan, Jiawei, Liu, Ning, Sun, Zimin, Liu, Huilan, Peng, Xiaojun, Hao, Yingchan, Zheng, Nan, Wu, Quan
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731804/
https://ncbi.nlm.nih.gov/pubmed/26822725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19926
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