Quantitative Analysis of Global Proteome and Lysine Acetylome Reveal the Differential Impacts of VPA and SAHA on HL60 Cells

Valproic acid (VPA) and suberoylanilide hydroxamic acid (SAHA) are both HDAC inhibitors (HDACi). Previous studies indicated that both inhibitors show therapeutic effects on acute myeloid leukaemia (AML), while the differential impacts of the two different HDACi on AML treatment still remains elusive...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Zhu, Xiaoyu, Liu, Xin, Cheng, Zhongyi, Zhu, Jun, Xu, Lei, Wang, Fengsong, Qi, Wulin, Yan, Jiawei, Liu, Ning, Sun, Zimin, Liu, Huilan, Peng, Xiaojun, Hao, Yingchan, Zheng, Nan, Wu, Quan
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731804/
https://ncbi.nlm.nih.gov/pubmed/26822725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19926
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