Hepatocyte TRAF3 promotes insulin resistance and type 2 diabetes in mice with obesity

OBJECTIVE: Metabolic inflammation is believed to promote insulin resistance and type 2 diabetes progression in obesity. TRAF3, a cytoplasmic signaling protein, has been known to mediate/modulate cytokine signaling in immune cells. The goal is to define the metabolic function of hepatic TRAF3 in the...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Chen, Zheng, Canet, Mark J., Sheng, Liang, Jiang, Lin, Xiong, Yi, Yin, Lei, Rui, Liangyou
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731737/
https://ncbi.nlm.nih.gov/pubmed/26909311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2015.09.013
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