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SH2B1 in β-Cells Promotes Insulin Expression and Glucose Metabolism in Mice

Insulin deficiency drives the progression of both type 1 and type 2 diabetes. Pancreatic β-cell insulin expression and secretion are tightly regulated by nutrients and hormones; however, intracellular signaling proteins that mediate nutrient and hormonal regulation of insulin synthesis and secretion...

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書誌詳細
主要な著者: Chen, Zheng, Morris, David L., Jiang, Lin, Liu, Yong, Rui, Liangyou
フォーマット: Artigo
言語:Inglês
出版事項: Endocrine Society 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4004774/
https://ncbi.nlm.nih.gov/pubmed/24645678
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1333
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