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SH2B1 in β-Cells Promotes Insulin Expression and Glucose Metabolism in Mice
Insulin deficiency drives the progression of both type 1 and type 2 diabetes. Pancreatic β-cell insulin expression and secretion are tightly regulated by nutrients and hormones; however, intracellular signaling proteins that mediate nutrient and hormonal regulation of insulin synthesis and secretion...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Endocrine Society
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4004774/ https://ncbi.nlm.nih.gov/pubmed/24645678 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/me.2013-1333 |
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