تحميل...
SIRT1 Activity Is Linked to Its Brain Region-Specific Phosphorylation and Is Impaired in Huntington’s Disease Mice
Huntington’s disease (HD) is a neurodegenerative disorder for which there are no disease-modifying treatments. SIRT1 is a NAD(+)-dependent protein deacetylase that is implicated in maintaining neuronal health during development, differentiation and ageing. Previous studies suggested that the modulat...
محفوظ في:
| الحاوية / القاعدة: | PLoS One |
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| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Public Library of Science
2016
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731418/ https://ncbi.nlm.nih.gov/pubmed/26815359 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145425 |
| الوسوم: |
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