The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats

BACKGROUND AND PURPOSE: Ischemic stroke provokes severe brain damage and remains a predominant disease in industrialized countries. The coagulation factor XII (FXII)-driven contact activation system plays a central, but not yet fully defined pathogenic role in stroke development. Here, we investigat...

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Detalhes bibliográficos
Publicado no:PLoS One
Principais autores: Krupka, Jennifer, May, Frauke, Weimer, Thomas, Pragst, Ingo, Kleinschnitz, Christoph, Stoll, Guido, Panousis, Con, Dickneite, Gerhard, Nolte, Marc W.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731395/
https://ncbi.nlm.nih.gov/pubmed/26815580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146783
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