New Infestin-4 Mutants with Increased Selectivity against Factor XIIa

Factor XIIa (fXIIa) is a serine protease that triggers the coagulation contact pathway and plays a role in thrombosis. Because it interferes with coagulation testing, the need to inhibit fXIIa exists in many cases. Infestin-4 (Inf4) is a Kazal-type inhibitor of fXIIa. Its specificity for fXIIa can b...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Kolyadko, Vladimir N., Lushchekina, Sofya V., Vuimo, Tatiana A., Surov, Stepan S., Ovsepyan, Ruzanna A., Korneeva, Vera A., Vorobiev, Ivan I., Orlova, Nadezhda A., Minakhin, Leonid, Kuznedelov, Konstantin, Severinov, Konstantin V., Ataullakhanov, Fazoil I., Panteleev, Mikhail A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4684401/
https://ncbi.nlm.nih.gov/pubmed/26670620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144940
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker