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Mapping Proteome-Wide Interactions of Reactive Chemicals Using Chemoproteomic Platforms

A large number of pharmaceuticals, endogenous metabolites, and environmental chemicals act through covalent mechanisms with protein targets. Yet, their specific interactions with the proteome still remain poorly defined for most of these reactive chemicals. Deciphering direct protein targets of reac...

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Библиографические подробности
Опубликовано в: :Curr Opin Chem Biol
Главные авторы: Counihan, Jessica L., Ford, Breanna, Nomura, Daniel K.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731263/
https://ncbi.nlm.nih.gov/pubmed/26647369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.11.007
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