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Mapping Proteome-Wide Interactions of Reactive Chemicals Using Chemoproteomic Platforms

A large number of pharmaceuticals, endogenous metabolites, and environmental chemicals act through covalent mechanisms with protein targets. Yet, their specific interactions with the proteome still remain poorly defined for most of these reactive chemicals. Deciphering direct protein targets of reac...

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Pubblicato in:Curr Opin Chem Biol
Autori principali: Counihan, Jessica L., Ford, Breanna, Nomura, Daniel K.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731263/
https://ncbi.nlm.nih.gov/pubmed/26647369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.11.007
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