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Mapping Proteome-Wide Interactions of Reactive Chemicals Using Chemoproteomic Platforms

A large number of pharmaceuticals, endogenous metabolites, and environmental chemicals act through covalent mechanisms with protein targets. Yet, their specific interactions with the proteome still remain poorly defined for most of these reactive chemicals. Deciphering direct protein targets of reac...

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Detalles Bibliográficos
Publicado en:Curr Opin Chem Biol
Autores principales: Counihan, Jessica L., Ford, Breanna, Nomura, Daniel K.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731263/
https://ncbi.nlm.nih.gov/pubmed/26647369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.11.007
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