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Mapping Proteome-Wide Interactions of Reactive Chemicals Using Chemoproteomic Platforms
A large number of pharmaceuticals, endogenous metabolites, and environmental chemicals act through covalent mechanisms with protein targets. Yet, their specific interactions with the proteome still remain poorly defined for most of these reactive chemicals. Deciphering direct protein targets of reac...
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Publicat a: | Curr Opin Chem Biol |
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Autors principals: | , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731263/ https://ncbi.nlm.nih.gov/pubmed/26647369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2015.11.007 |
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