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Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma

Klotho, an anti-aging gene, has recently been shown to contribute to human hepatic tumorigenesis. In addition, it is known that Wnt signaling is antagonized by the protein klotho. Because augmented Wnt signaling has an important role in tumorigenesis of human hepatocellular carcinoma (HCC), we studi...

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Bibliografiska uppgifter
I publikationen:Lab Invest
Huvudupphovsmän: Tang, Xiaowei, Wang, Yun, Fan, Zhining, Ji, Guozhong, Wang, Min, Lin, Jie, Huang, Shu, Meltzer, Stephen J
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731258/
https://ncbi.nlm.nih.gov/pubmed/26237271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.86
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