Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma

Klotho, an anti-aging gene, has recently been shown to contribute to human hepatic tumorigenesis. In addition, it is known that Wnt signaling is antagonized by the protein klotho. Because augmented Wnt signaling has an important role in tumorigenesis of human hepatocellular carcinoma (HCC), we studi...

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Bibliografske podrobnosti
izdano v:Lab Invest
Main Authors: Tang, Xiaowei, Wang, Yun, Fan, Zhining, Ji, Guozhong, Wang, Min, Lin, Jie, Huang, Shu, Meltzer, Stephen J
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731258/
https://ncbi.nlm.nih.gov/pubmed/26237271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.86
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