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Klotho: a tumor suppressor and modulator of the Wnt/β-catenin pathway in human hepatocellular carcinoma

Klotho, an anti-aging gene, has recently been shown to contribute to human hepatic tumorigenesis. In addition, it is known that Wnt signaling is antagonized by the protein klotho. Because augmented Wnt signaling has an important role in tumorigenesis of human hepatocellular carcinoma (HCC), we studi...

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Detalhes bibliográficos
Publicado no:Lab Invest
Main Authors: Tang, Xiaowei, Wang, Yun, Fan, Zhining, Ji, Guozhong, Wang, Min, Lin, Jie, Huang, Shu, Meltzer, Stephen J
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731258/
https://ncbi.nlm.nih.gov/pubmed/26237271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/labinvest.2015.86
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