DEPOSITION OF 5-METHYLCYTOSINE ON ENHANCER RNAs ENABLES THE COACTIVATOR FUNCTION OF PGC-1α

The Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) is a transcriptional co-activator that plays a central role in adapted metabolic responses. PGC-1α is dynamically methylated and unmethylated at the residue K779 by the methyltransferase SET7/9 and the Lysine Specific...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Cell Rep
Autori principali: Aguilo, Francesca, Li, SiDe, Balasubramaniyan, Natarajan, Sancho, Ana, Benko, Sabina, Zhang, Fan, Vashisht, Ajay, Rengasamy, Madhumitha, Andino, Blanca, Chen, Chih-hung, Zhou, Felix, Qian, Chengmin, Zhou, Ming-Ming, Wohlschlegel, James A., Zhang, Weijia, Suchy, Frederick J., Walsh, Martin J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731243/
https://ncbi.nlm.nih.gov/pubmed/26774474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.043
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi