PGC-1 Coactivators Regulate MITF and the Tanning Response

The production of pigment by melanocytes tans the skin and protects against skin cancers. UV-exposed keratinocytes secrete α-MSH, which then activates melanin formation in melanocytes by inducing the microphthalmia-associated transcription factor (MITF). We show that PPAR-γ coactivator (PGC)-1α and...

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Detalhes bibliográficos
Main Authors: Shoag, Jonathan, Haq, Rizwan, Zhang, Mingfeng, Liu, Laura, Rowe, Glenn C., Jiang, Aihua, Koulisis, Nicole, Farrel, Caitlin, Amos, Christopher I., Wei, Qingyi, Lee, Jeffrey E., Zhang, Jiangwen, Kupper, Thomas S., Qureshi, Abrar A., Cui, Rutao, Han, Jiali, Fisher, David E., Arany, Zoltan
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753666/
https://ncbi.nlm.nih.gov/pubmed/23201126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.10.027
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