PGC-1 Coactivators Regulate MITF and the Tanning Response

The production of pigment by melanocytes tans the skin and protects against skin cancers. UV-exposed keratinocytes secrete α-MSH, which then activates melanin formation in melanocytes by inducing the microphthalmia-associated transcription factor (MITF). We show that PPAR-γ coactivator (PGC)-1α and...

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Detaylı Bibliyografya
Asıl Yazarlar: Shoag, Jonathan, Haq, Rizwan, Zhang, Mingfeng, Liu, Laura, Rowe, Glenn C., Jiang, Aihua, Koulisis, Nicole, Farrel, Caitlin, Amos, Christopher I., Wei, Qingyi, Lee, Jeffrey E., Zhang, Jiangwen, Kupper, Thomas S., Qureshi, Abrar A., Cui, Rutao, Han, Jiali, Fisher, David E., Arany, Zoltan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3753666/
https://ncbi.nlm.nih.gov/pubmed/23201126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.10.027
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