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DEPOSITION OF 5-METHYLCYTOSINE ON ENHANCER RNAs ENABLES THE COACTIVATOR FUNCTION OF PGC-1α
The Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1α) is a transcriptional co-activator that plays a central role in adapted metabolic responses. PGC-1α is dynamically methylated and unmethylated at the residue K779 by the methyltransferase SET7/9 and the Lysine Specific...
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| izdano v: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2016
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731243/ https://ncbi.nlm.nih.gov/pubmed/26774474 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.043 |
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