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Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1
Histone demethylase upregulation has been observed in human cancers, yet it is unknown whether this is a bystander event or a driver of tumorigenesis. We found that overexpression of lysine-specific demethylase 4A (KDM4A, also known as JMJD2A) was positively correlated with Gleason score and metasta...
שמור ב:
| הוצא לאור ב: | J Clin Invest |
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| Main Authors: | , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Clinical Investigation
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731184/ https://ncbi.nlm.nih.gov/pubmed/26731476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78132 |
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