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Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1
Histone demethylase upregulation has been observed in human cancers, yet it is unknown whether this is a bystander event or a driver of tumorigenesis. We found that overexpression of lysine-specific demethylase 4A (KDM4A, also known as JMJD2A) was positively correlated with Gleason score and metasta...
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Publicado no: | J Clin Invest |
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Main Authors: | , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Clinical Investigation
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4731184/ https://ncbi.nlm.nih.gov/pubmed/26731476 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI78132 |
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