Toll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

The nature and role of the intestinal leukocytes in necrotizing enterocolitis (NEC), a severe disease affecting premature infants, remain unknown. We now show that the intestine in mouse and human NEC is rich in lymphocytes that are required for NEC development, as recombination activating gene 1–de...

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Vydáno v:J Clin Invest
Hlavní autoři: Egan, Charlotte E., Sodhi, Chhinder P., Good, Misty, Lin, Joyce, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Ma, Congrong, Branca, Maria F., Weyandt, Samantha, Fulton, William B., Niño, Diego F., Prindle, Thomas, Ozolek, John A., Hackam, David J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731173/
https://ncbi.nlm.nih.gov/pubmed/26690704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83356
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