Toll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

The nature and role of the intestinal leukocytes in necrotizing enterocolitis (NEC), a severe disease affecting premature infants, remain unknown. We now show that the intestine in mouse and human NEC is rich in lymphocytes that are required for NEC development, as recombination activating gene 1–de...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Egan, Charlotte E., Sodhi, Chhinder P., Good, Misty, Lin, Joyce, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Ma, Congrong, Branca, Maria F., Weyandt, Samantha, Fulton, William B., Niño, Diego F., Prindle, Thomas, Ozolek, John A., Hackam, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731173/
https://ncbi.nlm.nih.gov/pubmed/26690704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83356
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