Toll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

The nature and role of the intestinal leukocytes in necrotizing enterocolitis (NEC), a severe disease affecting premature infants, remain unknown. We now show that the intestine in mouse and human NEC is rich in lymphocytes that are required for NEC development, as recombination activating gene 1–de...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Clin Invest
Prif Awduron: Egan, Charlotte E., Sodhi, Chhinder P., Good, Misty, Lin, Joyce, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Ma, Congrong, Branca, Maria F., Weyandt, Samantha, Fulton, William B., Niño, Diego F., Prindle, Thomas, Ozolek, John A., Hackam, David J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731173/
https://ncbi.nlm.nih.gov/pubmed/26690704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83356
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