Toll-like receptor 4–mediated lymphocyte influx induces neonatal necrotizing enterocolitis

The nature and role of the intestinal leukocytes in necrotizing enterocolitis (NEC), a severe disease affecting premature infants, remain unknown. We now show that the intestine in mouse and human NEC is rich in lymphocytes that are required for NEC development, as recombination activating gene 1–de...

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Publicado en:J Clin Invest
Autores principales: Egan, Charlotte E., Sodhi, Chhinder P., Good, Misty, Lin, Joyce, Jia, Hongpeng, Yamaguchi, Yukihiro, Lu, Peng, Ma, Congrong, Branca, Maria F., Weyandt, Samantha, Fulton, William B., Niño, Diego F., Prindle, Thomas, Ozolek, John A., Hackam, David J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731173/
https://ncbi.nlm.nih.gov/pubmed/26690704
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83356
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