TDP-43 functions within a network of hnRNP proteins to inhibit the production of a truncated human SORT1 receptor

The aggregation and mislocalization of RNA-binding proteins leads to the aberrant regulation of RNA metabolism and is a key feature of many neurodegenerative diseases, including amyotrophic lateral sclerosis and frontotemporal dementia. However, the pathological consequences of abnormal deposition o...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Mohagheghi, Fatemeh, Prudencio, Mercedes, Stuani, Cristiana, Cook, Casey, Jansen-West, Karen, Dickson, Dennis W., Petrucelli, Leonard, Buratti, Emanuele
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731020/
https://ncbi.nlm.nih.gov/pubmed/26614389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv491
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