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Two-pore channels at the intersection of endolysosomal membrane traffic

Two-pore channels (TPCs) are ancient members of the voltage-gated ion channel superfamily that localize to acidic organelles such as lysosomes. The TPC complex is the proposed target of the Ca(2 +)-mobilizing messenger NAADP, which releases Ca(2 +) from these acidic Ca(2 +) stores. Whereas details o...

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Bibliografiske detaljer
Udgivet i:Biochem Soc Trans
Main Authors: Marchant, Jonathan S., Patel, Sandip
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4730950/
https://ncbi.nlm.nih.gov/pubmed/26009187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20140303
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