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Two-pore channels at the intersection of endolysosomal membrane traffic
Two-pore channels (TPCs) are ancient members of the voltage-gated ion channel superfamily that localize to acidic organelles such as lysosomes. The TPC complex is the proposed target of the Ca(2 +)-mobilizing messenger NAADP, which releases Ca(2 +) from these acidic Ca(2 +) stores. Whereas details o...
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| Veröffentlicht in: | Biochem Soc Trans |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4730950/ https://ncbi.nlm.nih.gov/pubmed/26009187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20140303 |
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